Monoclonal antibodies are derived from hybridoma cell lines, created by fusing mouse antibody producing B lymphocytes with mouse myeloma cells or are derived from a human cell line through EBV transformation. Each hybridoma cell line produces homogenous antibodies of only one immunoglobulin class, which are identical in their chemical structure and immunological activity.
Human red blood cells are classified as Rho (D) positive and Rho (D) negative depending upon the presence or absence of D (Rho) antigen on them. Approximately 85% of the Caucasian population are Rho (D) positive. The Du phenotype is a traditional definition to describe the weak / partial D’s that can be detected with Anti-D (Rho) (IgM+IgG). About 60% of the Du (weak / partial D’s) may react with Anti-D (Rho) (IgM+IgG) in slide tests and about 90% may be detected by tube technique.
But I must explain to you how all this mistaken idea of denouncing pleasure and praising pain was born and I will give you a complete account of the system, and expound the actual teachings of the great explorer of the truth, the master-builder of human happiness. No one rejects, dislikes, or avoids pleasure itself, because it is pleasure, but because those who do not know how to pursue pleasure rationally encounter consequences that are extremely painful.
