Monoclonal antibodies are derived from hybridoma cell lines, created by fusing mouse antibody producing B lymphocytes with mouse myeloma cells. Each hybridoma cell line produces homogenous antibodies of only one immunoglobulin class, which are identical in their chemical structure and immunological activity.
Human red blood cell antigens can be divided into four groups A, B, AB and O depending on the presence or absence of the corresponding antigens on the red blood cells.
Approximately 41% of the Caucasian population have the A Antigen, 9% have the B Antigen, 4% have both A and B antigens, while the remaining have neither the A nor the B antigen.
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